Zometa (Zoledronic Acid) 5 mg/100 ml Concentrate Vial Buy Online

 Zometa (Zoledronic Acid) 5 mg/100 ml Concentrate Vial Buy Online
Product Code: Zoledronate monohydrate
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 Zometa (Zoledronic Acid) 5 mg/100 ml Concentrate Vial Buy Online


How does Zometa work? What will it do for me?

Zoledronic acid (Zoledronate monohydrate) belongs to the family of medications known as bisphosphonates. It is used to treat Paget's disease of the bone. It is also used to treat osteoporosis in men, to treat and prevent osteoporosis in postmenopausal women, and to treat and prevent osteoporosis caused by steroid medications. 

Normally, the body maintains a balance between the processes of breaking down bone and building it up. In Paget's disease and osteoporosis, this balance becomes disturbed so that too much bone is being broken down. Zoledronic acid works by restoring the balance between the rate of bone breakdown and buildup.

Zometa may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested Zometa for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop receiving Zometa without consulting your doctor.

How should I use Zometa?

For Paget's disease and for the prevention of osteoporosis in postmenopausal women, the recommended dose of zoledronic acid is 5 mg given as a one-time intravenous (into a vein) infusion.

For treatment of osteoporosis in men, and for treatment and prevention of osteoporosis caused by steroid medications, the recommended dose is 5 mg given as an intravenous (into a vein) infusion once a year. Infusions are given by a doctor or nurse over at least 15 minutes.

It is recommended that people taking Zometa take calcium and vitamin D supplements to prevent low blood calcium levels. Your doctor will recommend a dose of these supplements based on your needs.

On the day of the infusion, it is important to drink at least 500 mL (2 cups) of fluids before and after the treatment.

Many things can affect the dose of Zometa that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are receiving the medication without consulting your doctor.

It is important to receive Zometa exactly as recommended by your doctor. If you miss an appointment to receive zoledronic acid, contact your doctor as soon as possible to reschedule your appointment.

Zometa is stored at room temperature.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does Zometa come in?

Each bottle of ready-to-use sterile solution for intravenous infusion contains zoledronic acid 5 mg/100 mL monohydrate 5.330 mg (equivalent to 5 mg zoledronic acid on an anhydrous basis). Nonmedicinal ingredients: mannitol, sodium citrate, and water for injection. The clear plastic and siliconized glass vials have a chlorobutyl rubber stopper coated with a fluoro-polymer and contain no latex.

Who should NOT take Zometa?

Do not use zoledronic acid if you:

- are allergic to zoledronic acid or any ingredient of this medication
- are allergic to any other bisphosphonate medication (e.g., alendronate, etidronate)
- are pregnant or breast-feeding
- have decreased kidney function
- have low blood calcium levels that have not been corrected or vitamin D deficiency

What side effects are possible with Zometa?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

- bone, muscle, or joint pain
- constipation
- dizziness
- excessive sweating
- fever and chills
- flu-like symptoms (e.g., fever, chills, bone pain, or muscle and joint pain)
- headache
- heartburn
- nausea
- reduced sense of touch
- skin reaction at the injection site
- tiredness
- vomiting
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

- eye pain, redness, or inflammation
- mouth sores that do not heal
- sensitivity of the eyes to light
- signs of osteonecrosis of the jaw (e.g., swelling or gum infections, bad breath, poor healing of the gums, feeling of numbness or heaviness in the jaw)
- shortness of breath
- signs of low blood calcium levels (e.g., muscle spasms, tingling or numbness of the fingers and mouth, twitching, or memory loss)
- skin rash
- thigh or groin pain
- weakness

Stop taking Zometa and seek immediate medical attention if any of the following occur:

- difficulty breathing
- irregular heartbeat
- signs of kidney failure (e.g., weakness, tiredness, loss of appetite, puffy eyes, hand and feet, decreased urine production or changed urine colour)
- signs of a severe allergic reaction (e.g., hives; difficulty breathing; swelling of the mouth, lips, tongue, or throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for Zometa?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

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